Coronavirus (COVID-19) Update 33 with pulmonologist & critical care specialist Roger Seheult, MD of https://www.MedCram.com

Dr. Seheult illustrates how medications like remdesivir may work on a cellular level to stop viral replication. South Korea has now tested almost 200,000 people for COVID-19 as the rest of the world lags behind and may be experiencing “the tip of the confirmed coronavirus cases iceberg.”

PLEASE NOTE: This video was recorded on March 9, 2020. Our more recent COVID-19 updates can be accessed free at our website https://www.medcram.com/courses/coronavirus-outbreak-symptoms-treatment or here on YouTube: https://www.youtube.com/playlist?list=PLQ_IRFkDInv_zLVFTgXA8tW0Mf1iiuuM_

We’ve produced each COVID-19 video with the best information we could access at the time of recording. Naturally, some videos will contain information that has become outdated or replaced by better information or research.

That said, we believe each video contains concepts that have enduring value and reviewing how the response to COVID-19 has progressed over time may be of interest to you as well.

LINKS from this video:

https://www.worldometers.info/coronavirus/

https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6

https://www.nih.gov/news-events/news-releases/nih-clinical-trial-remdesivir-treat-covid-19-begins

https://aidsinfo.nih.gov/understanding-hiv-aids/glossary/568/phase-1-trial

https://www.jbc.org/content/early/2020/02/24/jbc.AC120.013056.full.pdf

Previous videos from this series:
– Coronavirus Epidemic Update 32: Important Data from South Korea, Can Zinc Help Prevent COVID-19? https://youtu.be/Eeh054-Hx1U
– Coronavirus Epidemic Update 31: Mortality Rate, Cleaning Products, A More/Less Severe Virus Strain? https://youtu.be/7YI2tOoVVpk
– Coronavirus Epidemic Update 30: More Global COVID-19 Outbreaks, Vitamin D May Aid Prevention: https://youtu.be/gmqgGwT6bw0
– Coronavirus Epidemic Update 29: Testing problems, mutations, COVID-19 in Washington & Iran: https://youtu.be/XjEacUyp4vY
– Coronavirus Epidemic Update 28: Practical Prevention Strategies, Patient Age vs. Case Fatality Rate: https://youtu.be/quDYb_x54DM
– Coronavirus Epidemic Update 27: Testing accuracy for COVID-19 (CT Scan vs. RT-PCR), California Cases and Coronavirus Los Angeles: https://youtu.be/xQwfuJgJ9lo
– Coronavirus Epidemic Update 26: Treatment Updates, Stock Markets, Germany & San Francisco, Pandemic? https://youtu.be/bV1CZxJ-uvU
– Coronavirus Epidemic Update 25: Vaccine Developments, Italy’s Response, and Mortality Rate Trends: https://youtu.be/UImSVhLLeGY
– Coronavirus Epidemic Update 24: Coronavirus Infections in Italy, Transmissibility, COVID-19 Symptoms: https://youtu.be/UImSVhLLeGY
– Coronavirus Epidemic Update 23: Infections in Kids & Pregnancy, South Korea, Spillover From Bats: https://youtu.be/JGhwAGiAnJo
– Coronavirus Epidemic Update 22: Spread Without Symptoms, Cruise Quarantine, Asymptomatic Testing: https://youtu.be/OqpHvK0XADY
– Coronavirus Epidemic Update 21: Antibodies, Case Fatality, Clinical Recommendations, 2nd Infections?: https://youtu.be/9BYaywITXYk
– Coronavirus Epidemic Update 20: Misinformation Spread, Infection Severity, Cruise Ship, Origins: https://youtu.be/Ka48UZDDzLY
– Coronavirus Epidemic Update 19: Treatment and Medication Clinical Trials: https://youtu.be/4HK9QEy1KJ8
– Coronavirus Epidemic Update 18: Cellphone Tracking, Increase in Hospitalizations, More Sleep Tips: https://youtu.be/vE4pBkslqS4
– Coronavirus Epidemic Update 17: Spike in Confirmed Cases, Fighting Infections with Sleep (COVID-19): https://youtu.be/wlbM6VVkVZM
– Coronavirus Epidemic Update 16: Strengthening Your Immune Response to Viral Infections (COVID-19): https://youtu.be/qqZYEgREuZ8
– Coronavirus Epidemic Update 15: Underreporting, Prevention, 24 Day Incubation? (COVID19) https://youtu.be/o804wu5h_ms
– Coronavirus Epidemic Update 14: Hospital spread of infection, WHO allowed in China, N-95 masks: https://youtu.be/pDnmHu8x9C4
– Coronavirus Epidemic Update 13: Li Wenliang, nCoV vs Influenza, Dip in Daily Cases, Spread to Canada: https://youtu.be/0UgrPgJdzp0
– Coronavirus Epidemic Update 12: Unsupported Theories, Pneumonia, ACE2 & nCoV: https://youtu.be/GT3_A1bf9pU
– Coronavirus Epidemic Update 11: Antiviral Drugs, Treatment Trials for nCoV (Remdesivir, Chloroquine): https://youtu.be/pfGpdFNHoqQ
– Coronavirus Epidemic Update 10: New Studies, Transmission, Spread from Wuhan, Prevention (2019-nCoV): https://youtu.be/gPwfiQgGsFo
– Coronavirus Epidemic Update 9: Fecal-Oral Transmission, Recovery vs Death Rate: https://youtu.be/8Hjy3UfaTSc

– How Coronavirus Kills: Acute Respiratory Distress Syndrome (ARDS) & Treatment: https://youtu.be/okg7uq_HrhQ

Speaker: Roger Seheult, MD
Produced by Kyle Allred, PA

MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
#Coronavirus #COVID19 #SARSCoV2

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Obtaining a best possible medication history (BPMH) is an important first step in medication reconciliation. But what are the best strategies and approaches for getting a BPMH?
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B.Pharmacy 4th Semester- Pharmacology- Unit 01 and 02- https://www.youtube.com/watch?v=d44onkttxTc&list=PLtEqsPSBZlXuwf74dIoGzz6cLLkoWiEjR
B.Pharmacy 4th Semester- Pharmacology- Unit- 03- https://www.youtube.com/watch?v=xhawgAdtgQM&list=PLtEqsPSBZlXu_UkZF1sdE341ebm7G-xsN

Route of drug administration is the medium in which any drug is introduced into the body for its action. there are several routes of administration for the drug, like oral, sublingual, buccal, topical, parenteral, transdermal, subcutaneous, intramuscular, intravenous, vaginal and rectal.

There are various routes of administration available, each of which has associated advantages and disadvantages. All the routes of drug administration need to be understood in terms of their implications for the effectiveness of the drug therapy and the patient’s experience of drug treatment.
Route of administration plays a very important role In the duration as well as the onset of action of any drug. This important factor should be in mind while considering the administration. #pushpendrapatel#solutionpharmacy

Different route of drug administrations explained in this video are-
1- oral route of drug administration
2-Buccal route of drug administration
3- Sublingual route of drug administration
4-Parenteral route of drug administration
5-Intramuscular route of drug administration
6- Intravenous route of drug administration
7- Subcutaneous route of drug administration
8- Topical route of drug administration
9- Transdermal route of drug administration
10- Rectal route of drug administration
11- Vaginal route of drug administration

Get in touch with a solution by just clicking following links-

Facebook page- https://www.facebook.com/pharmavideo/
Facebook Group- https://www.facebook.com/groups/solutionpharamcy
Instagram- https://www.instagram.com/solutionpharmacy/
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B.Pharmacy 4th Semester- Pharmacology- Unit 01 and 02- https://www.youtube.com/watch?v=d44onkttxTc&list=PLtEqsPSBZlXuwf74dIoGzz6cLLkoWiEjR
B.Pharmacy 4th Semester- Pharmacology- Unit- 03- https://www.youtube.com/watch?v=xhawgAdtgQM&list=PLtEqsPSBZlXu_UkZF1sdE341ebm7G-xsN

Pharmacokinetics is currently defined as the study of the
time course of drug absorption, distribution, metabolism, and excretion. Clinical pharmacokinetics is the application of pharmacokinetic principles to the safe and effective therapeutic management of drugs in an individual patient. Pharmacokinetics influences the decided route of administration for a specific medication, the amount and frequency of each dose and its dosing intervals.

Pharmacokinetics of a drug depends on patient-related factors as well as on the drug’s chemical properties. Some patient-related factors (eg, renal function, genetic makeup, sex, age) can be used to predict the pharmacokinetic parameters in populations. For example, the half-life of some drugs, especially those that require both metabolism and excretion, may be remarkably long in the elderly

Before drugs can be clinically effective, they must be absorbed. Absorption is the process of a drug moving from its site of delivery into the bloodstream. The chemical composition of a drug, as well as the environment into which a drug is placed, work together to determine the rate and extent of drug absorption. Absorption involves several phases. First, the drug needs to be introduced via some route of administration (oral, topical-dermal, etc.) and in a specific dosage form such as a tablet, capsule, solution and so on. Drug absorption is determined by the drug’s physicochemical properties, formulation, and route of administration.

Pharmacokinetic- “What does BODY 1 do to the DRUG 2” we have simple interchanged the BODY and DRUG to make a definition. And as per the definition, our body responds to any drug by giving ADME effects.
1. A Stands for – Absorption
2. D stands for – Distribution
3. M stands for – Metabolism
4. E stands for- Elimination
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Very cool video of the first High Powered launch of the Tenochtitlan. This rocket weighs less than a pound so the H115 is a lot of motor for it!

Unfortunately, video quality is reduced due to plastic lens protection on the rocket. However, this is still a great video! Lens will be replaced & corrected prior to next launch.

Stats:
Length: 35 7/8″
Diameter: 2 5/8″
Mass with motor: 21.8oz
Stability: 1.4 Calipers
Motor: Aerotech H115DM-14A
Estimated Gs: 19.6 iPhone maxes at 7.2.
Phone: iPhone 6 (has barometer)
Video: 1080p vertical.
Resolution greatly reduced by plastic protection cover.
Will fix prior to next launch.

Special Thanks:

Ground zero launch video:
Eric Zsolczai
Photos:
Freddy Willems
Thea Mathen
Recovery team:
Atom and Scott

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Grab our free cheatsheet covering the 50 most commonly prescribed medications right here: http://NRSNG.com/50meds
Listen to all the episodes at: https://www.nrsng.com/medmaster-podcast/

View the blog post here: https://www.nrsng.com/haloperidol/

Haloperidol

Generic Name: haloperidol

Trade Name: Haldol

Indication: Schizophrenia, mania, aggressive and agitated patient

Action: Alters the effect of dopamine

Therapeutic Class: Antipsychotic

Pharmacologic Class: butyrophenones

Nursing Considerations
 extrapyramidal symptoms, tardive dyskinesia
 use caution in QT prolongation
 may cause seizures, constipation, dry mouth, agranulosytosis
 assess for hallucinations
 monitor hemodynamics
 monitor for neuroleptic malignant syndrome (fever, muscular rigidity, altered mental status, and autonomic dysfunction)
 monitor CBC with differential

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Here’s Shilika’s first video on Medicowesome 🙂
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Your medication Gabapentin

Gabapentin, also known by the brand names: Neurontin and Gralise.

Gabapentin comes in oral solution, oral suspension, tablet, and capsule dosage forms.

Gabapentin is most commonly used to treat seizures and painful nerve diseases. No matter what your doctor has you taking it for, gabapentin is usually taken by mouth with or without food most commonly 2 to 3 times a day. If upset stomach occurs take gabapentin with food. Do not take antacids within two hours of this medication. If you take the capsule, swallow the capsule whole and take with a full glass of water. If you are taking Gralise, take with the evening meal and swallow whole. To receive the greatest benefit, do not miss doses. If you miss a dose, take the missed dose as soon as you think about it. If it is close to time for your next dose, skip the missed dose and resume your normal dosing schedule. Do not take 2 doses at the same time or extra doses. If you have never taken gabapentin before, take your first dose at bedtime to avoid the feelings of tiredness and dizziness.

Some common side effects with gabapentin include dizziness, drowsiness, tiredness, weakness, loose stools, nausea and vomiting.
Some less common side effects include headache, abnormal thinking, swelling of the arms or legs, and weight gain.

While taking gabapentin, remember it is important to tell your doctor or pharmacist if:
• You have signs of an allergic reaction (rash, itching, swelling, tightness of the chest, etc.)
• You have signs of liver problems (dark urine, feeling tired, upset stomach, light-colored stools, or yellow skin or eyes
• You have signs of kidney problems (unable to pass urine, changes in how much urine is passed, blood in urine, or large weight gain)
• You have memory problems or memory loss
• You experience changes in eyesight, are feeling confused, or experience shakiness, shortness of breath, feeling very tired or weak, twitching, muscle pain or weakness
• To stop taking gabapentin because this medication should not be abruptly discontinued because of the possibility of increasing seizure frequency; therapy should be withdrawn gradually unless safety concerns require a more rapid withdrawal. Abrupt discontinuation with gabapentin has been associated with anxiety, diarrhea, headache, excessive sweating, sleeplessness, and nausea.

Gabapentin tablets and capsules need to be stored at room temperature in a dry place. Gabapentin liquid needs to be stored in the refrigerator. Use the measuring device received from the pharmacist or doctor for the oral solution.

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This video offers instruction on how to take a good medication history.

Follow Vanderbilt on Twitter: https://twitter.com/vanderbiltu, on Instagram: http://instagram.com/vanderbiltu and on Facebook: https://www.facebook.com/vanderbilt.

See all Vanderbilt social media at http://social.vanderbilt.edu.
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As part of Cleveland Clinic’s partnership with Parade magazine, endocrinologist, Betul Hatipoglu, MD, shares 5 tips for managing diabetes.
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Visit our website to learn more about using Nucleus content for patient engagement and content marketing: http://www.nucleushealth.com/

If you have type 2 diabetes, there are steps you can take that may help you keep your blood sugar within a normal range. Some ways to help manage your type 2 diabetes are explained.

ANH16178
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Http://intensivedietarymanagement.com
Diabetes is a curable disease. As a dietary disease, it demands a dietary treatment. The principles are outlined here.
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An international collaboration co-led by researchers at the Walter and Eliza Hall Institute has made a discovery that could enable therapeutic insulins to be made more effective than they currently are.

The findings will help to improve treatments for diabetes, a disease that impacts the lives of millions of people worldwide.

Published in Nature Communications, the study reveals the first definitive 3D image of how insulin successfully interacts with its receptor, a ‘gatekeeper’ for transmitting information into cells, in a process that is crucial for instructing cells to lower blood sugar levels in the body.

Understanding exactly what this process looks like can inform the design of faster-acting and longer-lasting insulin therapies.

Read more: https://www.wehi.edu.au/news/insulin-discovery-game-changer-improving-diabetes-treatments
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